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  1. 20 医学系研究科・医学部
  2. 20C 本学関連学会刊行誌
  3. 20C1 秋田医学
  4. 第38巻2号

THE EFFECTS OF TRIAZOLAM AND RILMAZAFONE ON THE PHYSICAL AND COGNITIVE FUNCTIONS IN HEALTHY ELDERLY PERSONS

http://hdl.handle.net/10295/1831
http://hdl.handle.net/10295/1831
cf25b492-c623-41b3-9b6e-9e53902d31e5
名前 / ファイル ライセンス アクション
akitai38(63).pdf akitai38(63).pdf (750.5 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2012-01-23
タイトル
タイトル THE EFFECTS OF TRIAZOLAM AND RILMAZAFONE ON THE PHYSICAL AND COGNITIVE FUNCTIONS IN HEALTHY ELDERLY PERSONS
言語 en
言語
言語 eng
主題
言語 en
主題Scheme Other
主題 hypnotics
主題
言語 en
主題Scheme Other
主題 physical and cognitive functions
主題
言語 en
主題Scheme Other
主題 elders
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
作成者 Inomata, Shoko

× Inomata, Shoko

en Inomata, Shoko

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Ito, Sachiko U

× Ito, Sachiko U

en Ito, Sachiko U

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Wakasa, Masahiko

× Wakasa, Masahiko

en Wakasa, Masahiko

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Osawa, Yukihiko

× Osawa, Yukihiko

en Osawa, Yukihiko

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Shimizu, Kazumi

× Shimizu, Kazumi

en Shimizu, Kazumi

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Ito, Wakako

× Ito, Wakako

en Ito, Wakako

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Kanbayashi, Takashi

× Kanbayashi, Takashi

en Kanbayashi, Takashi

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Shimizu, Tetsuo

× Shimizu, Tetsuo

en Shimizu, Tetsuo

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内容記述
内容記述タイプ Abstract
内容記述 The purpose of this study is to investigate whether often used hypnotics are safe or not to elderly people by evaluating the early morning effects and residual effects on the physical and cognitive functions after hypnotic administration. Fourteen healthy elders (3 male, 11 female ; mean age 64 years) took part in the study. Triazolam 0.125 mg, rilmazafone hydrochloride 1 mg or placebo was orally given to each subject before going to bed (11 pm). Objective evaluations including 1. Total Sway Path test (opened and closed eye) 2. Functional Reach test 3. Timed Up and Go test 4. Simply Discriminatory Reaction test 5. Critical Flicker Fusion test 6. Short-Term Memory test were done at 10 pm (an hour before subjects went to bed), 4 am, 6 am, 10 am and 2 pm. Among all evaluations for the physical and cognitive functions, main effects between medicines were only seen in the Total Sway Path test, which is the indicator for static balance ability. When eyes were opened, trembling was significantly small in the rilmazafon group compared to the placebo group (p=0.04). In this study, the hypnotics did not affect physical and cognitive functions for healthy elders. Further studies using an interdisciplinary approach with different professionals such nurses, physical therapists, pharmacists and physicians are needed for evaluating the safety use of hypnotics in the elderly patients with insomnia.
言語 en
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
書誌情報 ja : 秋田医学

巻 38, 号 2, p. 63-69, 発行日 2011-12-01
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 03866106
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AN00009294
出版者
出版者 秋田医学会
言語 ja
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