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  1. 20 医学系研究科・医学部
  2. 20A 学術誌論文
  3. 20A1 雑誌掲載論文

Nature and Clinical Outcomes of Acute Hemorrhagic Rectal Ulcer

http://hdl.handle.net/10295/00006226
http://hdl.handle.net/10295/00006226
c69d4943-7d71-4c47-b601-1584842261e8
名前 / ファイル ライセンス アクション
iA_2022_83.pdf iA_2022_83.pdf (591.7 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2023-02-23
タイトル
タイトル Nature and Clinical Outcomes of Acute Hemorrhagic Rectal Ulcer
言語 en
言語
言語 eng
主題
主題Scheme Other
主題 acute hemorrhagic rectal ulcer
主題
主題Scheme Other
主題 lower gastrointestinal bleeding
主題
主題Scheme Other
主題 in-hospital mortality
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
作成者 Takahashi, Yasutaka

× Takahashi, Yasutaka

en Takahashi, Yasutaka

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Shimodaira, Yosuke

× Shimodaira, Yosuke

en Shimodaira, Yosuke

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Matsuhashi, Tamotsu

× Matsuhashi, Tamotsu

en Matsuhashi, Tamotsu

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Tsuji, Tsuyotoshi

× Tsuji, Tsuyotoshi

en Tsuji, Tsuyotoshi

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Fukuda, Sho

× Fukuda, Sho

en Fukuda, Sho

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Sugawara, Kae

× Sugawara, Kae

en Sugawara, Kae

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Saruta, Youhei

× Saruta, Youhei

en Saruta, Youhei

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Watanabe, Kenta

× Watanabe, Kenta

en Watanabe, Kenta

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Iijima, Katsunori

× Iijima, Katsunori

en Iijima, Katsunori

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内容記述
内容記述タイプ Abstract
内容記述 Acute hemorrhagic rectal ulcer (AHRU) is a relatively rare disease that can lead to massive hematochezia. Although AHRU is a potentially life-threatening disease, its characteristics and clinical course are not fully understood. In this study, the clinical features were compared between AHRU and lower gastrointestinal bleeding (LGIB) from other causes (non-AHRU). Then, risk factors for all-cause in-hospital mortality in patients with AHRU were identified. A total of 387 consecutive adult patients with LGIB who were managed at two tertiary academic hospitals in Akita prefecture in Japan were retrospectively enrolled. Subjects were divided into AHRU and non-AHRU groups according to the source of bleeding. Regression analyses were used to investigate significant associations, and the results were expressed as odds ratios (ORs) and 95% confidence intervals (CIs). AHRU was found as the bleeding source in 72 (18.6%) of the patients. In comparison to non-AHRU, having AHRU was significantly associated with in-hospital onset, age > 65 years, and systolic blood pressure < 90 mmHg. The AHRU group had a significantly higher in-hospital mortality rate in comparison to the non-AHRU group (18.0% vs. 8.3, p = 0.02), and hypoalbuminemia (<2.5 g/dL) was significantly associated with in-hospital mortality in the AHRU group (OR, 4.04; 95%CI, 1.11-14.9; p = 0.03). AHRU accounts for a substantial portion (18.6%) of LGIB in our area, where the aging rate is the highest in Japan. Since AHRU is a potentially life-threatening disease that requires urgent identification and management, further studies to identify robust risk factors associated with serious clinical outcomes are required.
言語 en
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
書誌情報 en : DIAGNOSTICS

巻 12, 号 10, 発行日 2022
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 2075-4418
出版者
出版者 MDPI
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.3390/diagnostics12102487
権利情報
権利情報 © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access
article distributed under the terms and conditions of the Creative Commons Attribution
(CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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