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  1. 20 医学系研究科・医学部
  2. 20A 学術誌論文
  3. 20A1 雑誌掲載論文

Neutrophil elastase in amniotic fluid as a predictor of preterm birth after emergent cervical cerclage

http://hdl.handle.net/10295/00006192
http://hdl.handle.net/10295/00006192
6e276684-136e-4156-96ec-5f15b60d778c
名前 / ファイル ライセンス アクション
iA_2022_57.pdf iA_2022_57.pdf (1.7 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2023-02-19
タイトル
タイトル Neutrophil elastase in amniotic fluid as a predictor of preterm birth after emergent cervical cerclage
言語 en
言語
言語 eng
主題
主題Scheme Other
主題 Amniotic fluid
主題
主題Scheme Other
主題 cervical cerclage
主題
主題Scheme Other
主題 glucose
主題
主題Scheme Other
主題 neutrophil elastase
主題
主題Scheme Other
主題 pregnancy
主題
主題Scheme Other
主題 premature birth
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
作成者 Hatakeyama, Yuko

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en Hatakeyama, Yuko

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Miura, Hiroshi

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en Miura, Hiroshi

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Sato, Akira

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en Sato, Akira

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Onodera, Yohei

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en Onodera, Yohei

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Sato, Naoki

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Shimizu, Dai

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Kumazawa, Yukiyo

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Sanada, Hiroyuki

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Hirano, Hideto

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Terada, Yukihiro

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内容記述
内容記述タイプ Abstract
内容記述 Introduction. The aim of this study was to investigate neutrophil elastase (NE) in amniotic fluid as a potential marker for predicting pregnancy continuation. Material and methods. We enrolled 34 pregnant women with bulging fetal membrane during the second trimester who underwent emergent cerclage after confirming the absence of intrauterine infection (amniotic fluid glucose >= 15 mg/dL). Amniotic fluid NE levels were compared between women who completed and did not complete 30, 34, and 36 weeks of gestation, and the optimal cut-off value for predicting pregnancy continuation was estimated. Moreover, the differences in the duration of continued pregnancy were compared between women with NE levels above and below the optimal cut-off value. Results. The optimal cut-off value for NE in amniotic fluid that predicted pregnancy continuation beyond 30, 34, and 36 weeks of gestation was 180 ng/mL; this cut-off value had a sensitivity, specificity, positive predictive value, and negative predictive value of 84.0, 77.8, 91.3, and 63.7% beyond 30 weeks of gestation; 87.5, 80.0, 91.5, and 72.3% beyond 34 weeks of gestation; and 85.0, 71.4, 80.9, and 76.9% beyond 36 weeks of gestation, respectively. The duration of continued pregnancy from emergent cerclage to delivery was significantly longer in women with amniotic fluid NE <180 ng/mL (95.1 +/- 5.4 days) than in women with amniotic fluid NE >= 180 ng/mL (44.8 +/- 14.3 days). Conclusion. The NE levels in amniotic fluid may serve as a useful marker for predicting the duration of continued pregnancy after cervical cerclage.
言語 en
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
書誌情報 en : Acta Obstetricia et Gynecologica Scandinavica

巻 95, 号 10, p. 1136-1142, 発行日 2016
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0001-6349
出版者
出版者 John Wiley and Sons Inc
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.1111/aogs.12928
権利情報
権利情報 ©2016 The Authors.Acta Obstetricia et Gynecologica Scandinavicapublished by John Wiley & Sons Ltdon behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).,95(2016) 1136–1142 This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use anddistribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
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