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Neutrophil elastase in amniotic fluid as a predictor of preterm birth after emergent cervical cerclage
http://hdl.handle.net/10295/00006192
http://hdl.handle.net/10295/000061926e276684-136e-4156-96ec-5f15b60d778c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
iA_2022_57.pdf (1.7 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2023-02-19 | |||||
| タイトル | ||||||
| タイトル | Neutrophil elastase in amniotic fluid as a predictor of preterm birth after emergent cervical cerclage | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 主題 | ||||||
| 主題Scheme | Other | |||||
| 主題 | Amniotic fluid | |||||
| 主題 | ||||||
| 主題Scheme | Other | |||||
| 主題 | cervical cerclage | |||||
| 主題 | ||||||
| 主題Scheme | Other | |||||
| 主題 | glucose | |||||
| 主題 | ||||||
| 主題Scheme | Other | |||||
| 主題 | neutrophil elastase | |||||
| 主題 | ||||||
| 主題Scheme | Other | |||||
| 主題 | pregnancy | |||||
| 主題 | ||||||
| 主題Scheme | Other | |||||
| 主題 | premature birth | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 作成者 |
Hatakeyama, Yuko
× Hatakeyama, Yuko× Miura, Hiroshi× Sato, Akira× Onodera, Yohei× Sato, Naoki× Shimizu, Dai× Kumazawa, Yukiyo× Sanada, Hiroyuki× Hirano, Hideto× Terada, Yukihiro |
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| 内容記述 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Introduction. The aim of this study was to investigate neutrophil elastase (NE) in amniotic fluid as a potential marker for predicting pregnancy continuation. Material and methods. We enrolled 34 pregnant women with bulging fetal membrane during the second trimester who underwent emergent cerclage after confirming the absence of intrauterine infection (amniotic fluid glucose >= 15 mg/dL). Amniotic fluid NE levels were compared between women who completed and did not complete 30, 34, and 36 weeks of gestation, and the optimal cut-off value for predicting pregnancy continuation was estimated. Moreover, the differences in the duration of continued pregnancy were compared between women with NE levels above and below the optimal cut-off value. Results. The optimal cut-off value for NE in amniotic fluid that predicted pregnancy continuation beyond 30, 34, and 36 weeks of gestation was 180 ng/mL; this cut-off value had a sensitivity, specificity, positive predictive value, and negative predictive value of 84.0, 77.8, 91.3, and 63.7% beyond 30 weeks of gestation; 87.5, 80.0, 91.5, and 72.3% beyond 34 weeks of gestation; and 85.0, 71.4, 80.9, and 76.9% beyond 36 weeks of gestation, respectively. The duration of continued pregnancy from emergent cerclage to delivery was significantly longer in women with amniotic fluid NE <180 ng/mL (95.1 +/- 5.4 days) than in women with amniotic fluid NE >= 180 ng/mL (44.8 +/- 14.3 days). Conclusion. The NE levels in amniotic fluid may serve as a useful marker for predicting the duration of continued pregnancy after cervical cerclage. | |||||
| 言語 | en | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 書誌情報 |
en : Acta Obstetricia et Gynecologica Scandinavica 巻 95, 号 10, p. 1136-1142, 発行日 2016 |
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| 収録物識別子 | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0001-6349 | |||||
| 出版者 | ||||||
| 出版者 | John Wiley and Sons Inc | |||||
| 関連情報 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1111/aogs.12928 | |||||
| 権利情報 | ||||||
| 権利情報 | ©2016 The Authors.Acta Obstetricia et Gynecologica Scandinavicapublished by John Wiley & Sons Ltdon behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).,95(2016) 1136–1142 This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use anddistribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. | |||||
