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  1. 20 医学系研究科・医学部
  2. 20A 学術誌論文
  3. 20A1 雑誌掲載論文

99mTc-GSA scintigraphy for assessing the functional volume ratio of the future liver remnant in the routine practice of liver resection

http://hdl.handle.net/10295/00006093
http://hdl.handle.net/10295/00006093
5a2339d4-1cb4-4915-baee-48da48773be5
名前 / ファイル ライセンス アクション
iA_2022_7.pdf iA_2022_7.pdf (1.4 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2022-10-27
タイトル
タイトル 99mTc-GSA scintigraphy for assessing the functional volume ratio of the future liver remnant in the routine practice of liver resection
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
作成者 Iida, Masatake

× Iida, Masatake

en Iida, Masatake

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Yamamoto, Yuzo

× Yamamoto, Yuzo

en Yamamoto, Yuzo

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Katoh, Hiroki

× Katoh, Hiroki

en Katoh, Hiroki

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Taniguchi, Naoto

× Taniguchi, Naoto

en Taniguchi, Naoto

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Abe, Yuki

× Abe, Yuki

en Abe, Yuki

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Kumagai, Kenta

× Kumagai, Kenta

en Kumagai, Kenta

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Uchinami, Hiroshi

× Uchinami, Hiroshi

en Uchinami, Hiroshi

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内容記述
内容記述タイプ Abstract
内容記述 Background
The significance of incorporating regional functional heterogeneity assessment by liver scintigraphy into the calculation of the future liver remnant has been reported. However, liver scintigraphy entails additional costs and radiation exposure. Nevertheless, studies describing when liver scintigraphy demonstrates an actual benefit over computed tomography liver volumetry are lacking. Thus, we evaluated the degree of agreement between future liver remnant % values calculated by technetium 99mTc diethylenetriaminepentaacetic acid-galactosyl human serum albumin scintigraphy (galactosyl human serum albumin–based future liver remnant %) and those by computed tomography volumetry and investigated the practical impact of performing regional functional heterogeneity assessment.

Methods
The Bland–Altman method was used to retrospectively analyze the agreement between computed tomography– and galactosyl human serum albumin–based future liver remnant % measurements in 84 patients.

Results
In ordinary patients with a computed tomography–based future liver remnant % greater than 50%, there was a good agreement between both measurements. However, in cases with a computed tomography–based future liver remnant % less than 40%, galactosyl human serum albumin–based measurements were significantly smaller than computed tomography–based values, with 88% of these patients exhibiting a galactosyl human serum albumin–based future liver remnant % less than 30%. After portal vein embolization, galactosyl human serum albumin–based measurements were primarily greater than or in agreement with computed tomography–based values, even in cases with a computed tomography–based future liver remnant % less than 40%.

Conclusion
Adding 99mTc diethylenetriaminepentaacetic acid-galactosyl human serum albumin scintigraphy to computed tomography liver volumetry is advised when deciding on hepatectomy in patients with a computed tomography–based future liver remnant % less than 50%. If the computed tomography–based future liver remnant % is smaller than 40%, it is strongly recommended to check future liver remnant % by 99mTc diethylenetriaminepentaacetic acid-galactosyl human serum albumin scintigraphy. In other cases, computed tomography–based future liver remnant % calculation alone can be regarded as the gold standard of safe hepatectomy.
言語 en
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
書誌情報 Surgery Open Science

巻 8, p. 1-8, 発行日 2022
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 25898450
出版者
出版者 Elsevier Inc.
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.sopen.2021.12.001
権利情報
権利情報 © 2022 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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