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  1. 20 医学系研究科・医学部
  2. 20A 学術誌論文
  3. 20A1 雑誌掲載論文

Outcomes of definitive chemoradiotherapy for stage iva (T4b vs. n4) esophageal squamous cell carcinoma based on the japanese classification system: A retrospective single-center study

http://hdl.handle.net/10295/00005747
http://hdl.handle.net/10295/00005747
a46d43e5-cb4f-427a-9e81-2fd81cc5d168
名前 / ファイル ライセンス アクション
iA_2021_25.pdf iA_2021_25 (445.3 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2021-08-10
タイトル
タイトル Outcomes of definitive chemoradiotherapy for stage iva (T4b vs. n4) esophageal squamous cell carcinoma based on the japanese classification system: A retrospective single-center study
言語 en
言語
言語 eng
主題
言語 en
主題Scheme Other
主題 esophageal squamous cell carcinoma
主題
言語 en
主題Scheme Other
主題 definitive chemoradiation therapy
主題
言語 en
主題Scheme Other
主題 external beam radiation therapy
主題
言語 en
主題Scheme Other
主題 locally advanced esophageal cancer
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
作成者 Wada, Yuki

× Wada, Yuki

en Wada, Yuki

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Anbai, Akira

× Anbai, Akira

en Anbai, Akira

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Takagi, Noriko

× Takagi, Noriko

en Takagi, Noriko

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Kumagai, Satoshi

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en Kumagai, Satoshi

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Okuyama, Eriko

× Okuyama, Eriko

en Okuyama, Eriko

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Nanjo, Hiroshi

× Nanjo, Hiroshi

en Nanjo, Hiroshi

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Sato, Yusuke

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en Sato, Yusuke

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Motoyama, Satoru

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en Motoyama, Satoru

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Hashimoto, Manabu

× Hashimoto, Manabu

en Hashimoto, Manabu

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内容記述
内容記述タイプ Abstract
内容記述 The differences in prognoses or progression patterns between T4b non-N4 and non-T4b N4 esophageal squamous cell carcinoma post chemoradiotherapy (CRT) is unclear. This study compared the outcomes of CRT for stage IVa esophageal squamous cell carcinoma according to T/N factors. We retrospectively identified 66 patients with stage IVa esophageal squamous cell carcinoma who underwent definitive CRT at our center between January 2009 and March 2013. The treatment outcomes, i.e., progression patterns, prognostic factors, and toxicities based on version 5.0 of the National Cancer Institute Common Terminology Criteria for Adverse Events, were studied. The patients (56 men and 10 women) had a median age of 67 (range: 37–87) years. The T/N classifications were T4b non-N4 (28/66), non-T4b N4 (24/66), and T4b N4 (14/66). Objective response was achieved in 57 patients (86.4%, (95% confidence interval, 74.6–94.1%)). There were no significant differences between the T/N groups in terms of overall survival, progression-free survival, and progression pattern. We found no significant differences in prognoses or progression patterns among patients with T4b non-N4, non-T4b N4, and T4b N4 esophageal squamous cell carcinoma. Thus, it seems impractical to modify CRT regimens based on T/N factors.
言語 en
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
書誌情報 en : Cancers

巻 13, 号 1, 発行日 2021
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 2072-6694
出版者
出版者 MDPI
言語 en
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://dx.doi.org/10.3390/cancers13010008
権利情報
言語 en
権利情報 Copyright: c2020 by the authors. LicenseeMDPI,Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the CreativeCommonsAttribution (CCBY) license (https://creativecommons.org/licenses/by/4.0/).
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