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  1. 20 医学系研究科・医学部
  2. 20A 学術誌論文
  3. 20A1 雑誌掲載論文

Current state of hypnotic use disorders: Results of a survey using the Japanese version of Benzodiazepine Dependence Self-Report Questionnaire

http://hdl.handle.net/10295/00005720
http://hdl.handle.net/10295/00005720
291896ea-0349-445f-94dc-f940b401aa5f
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iA_2021_3.pdf iA_2021_3 (388.0 kB)
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Item type 学術雑誌論文 / Journal Article(1)
公開日 2021-06-04
タイトル
タイトル Current state of hypnotic use disorders: Results of a survey using the Japanese version of Benzodiazepine Dependence Self-Report Questionnaire
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
作成者 Yamamoto, Mai

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Inada, Ken

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en Inada, Ken

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Enomoto, Minori

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en Enomoto, Minori

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Habukawa, Mitsunari

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en Habukawa, Mitsunari

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Hirose, Takahisa

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en Hirose, Takahisa

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Inoue, Yuichi

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Ishigooka, Jun

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en Ishigooka, Jun

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Kamei, Yuichi

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Kitajima, Tsuyoshi

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en Kitajima, Tsuyoshi

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Miyamoto, Masayuki

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Shinno, Hideto

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Nishimura, Katsuji

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Ozone, Motohiro

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Takeshima, Masahiro

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Suzuki, Mayumi

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Yamashita, Hidehisa

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Mishima, Kazuo

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内容記述
内容記述タイプ Abstract
内容記述 Aims Benzodiazepine receptor agonists (BZ-RAs) are frequently prescribed to treat insomnia; however, their long-term use is not recommended. To introduce an appropriate pharmaco-therapy, the current state and background factors of BZ-RAs' dependence must be elucidated. In this study, we developed a Japanese version of the Benzodiazepine Dependence Self-Report Questionnaire (Bendep-SRQ-J) and conducted a study of BZ-RAs' use disorder. Methods The Bendep-SRQ-J was created with permission from the original developer. Subjects were inpatients and outpatients receiving BZ-RAs between 2012 and 2013. Clinical data collected were Bendep-SRQ-J scores, sleep disorders for which BZ-RAs were prescribed, physical comorbidities, psychotropic drugs, and lifestyle factors. Logistic analysis was performed to extract factors associated with severe symptoms. Results Of the 707 patients prescribed BZ-RAs, 324 had voluntarily tapered or discontinued their drugs. Logistic analysis showed that the total number of drugs administered in the last 6 months correlated with both worsening of symptoms or conditions. This was more notable among younger patients, and the proportion of patients with severe symptoms or conditions increased with the increasing number of drugs. Conclusion Using the Bendep-SRQ-J, we elucidated the current state of BZ-RA dependence. Nearly half of the patients were non-compliant. The proportion of patients with severe symptoms or disease conditions increased with the increase in the number of drugs administered. These findings highlight the need for clinicians to be aware of the likelihood of benzodiazepine dependence, especially in young patients and patients prescribed multiple hypnotics.
言語 en
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
書誌情報 en : Neuropsychopharmacology Reports

巻 41, 号 1, p. 14-25, 発行日 2021-03
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 2574-173X
出版者
出版者 John Wiley & Sons
言語 en
関連情報
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.1002/npr2.12149
権利情報
言語 en
権利情報 © 2020 The Authors. Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Society of NeuropsychoPharmacology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
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