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  1. 20 医学部:School of Medicine
  2. 20C 本学関連学会刊行誌
  3. 20C1 秋田医学
  4. 第44巻3/4号

A COMPARISON OF THE THERAPEUTIC EFFICACY OF TRANSARTERIAL CHEMOEMBOLIZATION AND COMBINATION THERAPY WITH TRANSARTERIAL CHEMOEMBOLIZATION PLUS SORAFENIB FOR UNRESECTABLE HEPATOCELLULAR CARCINOMA

https://doi.org/10.20569/00003585
https://doi.org/10.20569/00003585
54983968-5951-440b-ae10-5fdce8cb0362
名前 / ファイル ライセンス アクション
akitai44_3_4(87).pdf akitai44_3_4(87) (617.9 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-07-05
タイトル
タイトル A COMPARISON OF THE THERAPEUTIC EFFICACY OF TRANSARTERIAL CHEMOEMBOLIZATION AND COMBINATION THERAPY WITH TRANSARTERIAL CHEMOEMBOLIZATION PLUS SORAFENIB FOR UNRESECTABLE HEPATOCELLULAR CARCINOMA
言語
言語 eng
キーワード
主題Scheme Other
主題 TACE
キーワード
主題Scheme Other
主題 sorafenib
キーワード
主題Scheme Other
主題 combination therapy
キーワード
主題Scheme Other
主題 unresectable HCC
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
ID登録
ID登録 10.20569/00003585
ID登録タイプ JaLC
著者 SUGIMOTO, Yuko

× SUGIMOTO, Yuko

WEKO 10213

SUGIMOTO, Yuko

Search repository
SATO, Wataru

× SATO, Wataru

WEKO 9471

SATO, Wataru

Search repository
SUZUKI, Toshiaki

× SUZUKI, Toshiaki

WEKO 4773

SUZUKI, Toshiaki

Search repository
MATSUZAWA, Hisanori

× MATSUZAWA, Hisanori

WEKO 10218

MATSUZAWA, Hisanori

Search repository
MINAMI, Shinichiro

× MINAMI, Shinichiro

WEKO 9476

MINAMI, Shinichiro

Search repository
TAKAHASHI, Kenichi

× TAKAHASHI, Kenichi

WEKO 10214

TAKAHASHI, Kenichi

Search repository
ARATA, Suguru

× ARATA, Suguru

WEKO 10212

ARATA, Suguru

Search repository
SHIBUYA, Tomomi

× SHIBUYA, Tomomi

WEKO 9470

SHIBUYA, Tomomi

Search repository
CHIBA, Mitsuru

× CHIBA, Mitsuru

WEKO 597

CHIBA, Mitsuru

Search repository
DOHMEN, Takahiro

× DOHMEN, Takahiro

WEKO 9472

DOHMEN, Takahiro

Search repository
OHSHIMA, Shigetoshi

× OHSHIMA, Shigetoshi

WEKO 9468

OHSHIMA, Shigetoshi

Search repository
TOZAWA, Tomoki

× TOZAWA, Tomoki

WEKO 9491

TOZAWA, Tomoki

Search repository
ISHIYAMA, Koichi

× ISHIYAMA, Koichi

WEKO 9490

ISHIYAMA, Koichi

Search repository
Hashimoto, Manabu

× Hashimoto, Manabu

WEKO 6408

Hashimoto, Manabu

Search repository
GOTO, Takashi

× GOTO, Takashi

WEKO 6135

GOTO, Takashi

Search repository
IIJIMA, Katsunori

× IIJIMA, Katsunori

WEKO 10221

IIJIMA, Katsunori

Search repository
内容記述(抄録)
内容記述タイプ Other
内容記述 [Background and Aims] The combination therapy of transarterial chemoembolization (TACE) plus sorafenib has been applied for unresectable hepatocellular carcinoma (HCC). However, its efficacy remains controversial, possibly due to the timing of the initiation of sorafenib treatment. We evaluated the efficacy of this combination therapy when sorafenib treatment was initiated soon after the patient recovered from the adverse events due to the initial TACE procedure. 
[Methods] This was a retrospective study at a single hospital. Twenty-three unresectable HCC cases who exceeded the up-to-seven criteria but who showed no major vascular invasion or extrahepatic metastasis were enrolled in this study. The patients were classified into two groups : Group C (n=7) received combination therapy ; Group T (n=16) received TACE as the sole therapy. The time-to-tumor progression (TTP) and overall survival (OS) of the two groups were compared. [Results] The median TTP in Groups C and T was 1,737 days and 422 days, respectively (p < 0.05). The median survival time (MST) after the initiation of each therapy in Groups C and T was 1,780 days and 371 days, respectively (p < 0.05). [Conclusion] The TTP and OS of patients with unresectable HCC who received TACE plus sorafenib (administered soon after the initial TACE procedure) were superior to those in patients who received TACE alone.
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
書誌情報 秋田医学
en : AKITA JOURNAL OF MEDICINE

巻 44, 号 3/4, p. 87-92, 発行日 2018-03
ISSN
収録物識別子タイプ ISSN
収録物識別子 03866106
NCID
収録物識別子タイプ NCID
収録物識別子 AN00009294
出版者
出版者 秋田医学会
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