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抗アレルギー作用を有する食品成分-地域食資源の探索と必須脂肪酸バランス改善食品の効果-
http://hdl.handle.net/10295/2101
http://hdl.handle.net/10295/2101660c540c-b91d-48b0-b704-d678de557e49
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
kbs68(7).pdf (3.2 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2013-05-10 | |||||||||
| タイトル | ||||||||||
| タイトル | 抗アレルギー作用を有する食品成分-地域食資源の探索と必須脂肪酸バランス改善食品の効果- | |||||||||
| その他のタイトル | ||||||||||
| その他のタイトル | Antiallergic Potential of Food Components: Research on the Regional Edible Plants and Effect of the Food Improved in Essential Fatty Acid Balance | |||||||||
| 言語 | ||||||||||
| 言語 | jpn | |||||||||
| 主題 | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Allergy | |||||||||
| 主題 | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Histamine | |||||||||
| 主題 | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | β-Hexosaminidase | |||||||||
| 主題 | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Leurotriene | |||||||||
| 主題 | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Linoleic acid | |||||||||
| 主題 | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | α-Linolenic acid | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | departmental bulletin paper | |||||||||
| 作成者 |
池本, 敦
× 池本, 敦
× IKEMOTO, Atsushi
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| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Antiallergic potentials of food components from the edible plants collected in Akita Prefecture were evaluated using RBL-2H3 rat mast cells. Several extracts from the plants inhibited β-hexosaminidase secretion. Their antiallergic effects were confirmed by further experiment on histamine release in antigen-antibody-stimulated RBL-2H3 cells. We found that two methanol extracts form Junsai (water shield, Brasenia schreberi) and Tonbiri (belvedere fruit, Kochia scoparia）suppressed histamine release (IC_50, 250μg/ml, respectively). N-3 fatty acid such as α-linolenic acid has antiallergic effects through the competitive inhibition of n-6 fatty acid metabolism and production of eicosanoid such as leukotrienes. Therefore we searched α-linolenate-rich beans or nuts from the regional food resources. However we did not found α-linolenate-rich food materials more than perilla seed oil We also made α-linolenate-rich ice cream supplemented with 10％(wt/wt) perilla oil and its antiallergic effect was evaluated using polymorphonuclear leukocytes from rats fed semipurified diets supplemented with the ice cream (20％, wt/wt). Compared with linoleate-rich ice cream supplemented with 10％(wt/wt) sesame oil, perilla ice cream significantly decreased both arachidonic acid content and leukotriene B_4 production in rat polymorphonuclear leukocytes. Thus, n-3 fatty acid-rich processed foods have antiallergic properties and essential fatty acid balance is important factor for the prevention of allergic symptoms. | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 書誌情報 |
秋田大学教育文化学部研究紀要 自然科学 巻 68, p. 7-16, 発行日 2013-03-31 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 13485296 | |||||||||
| NCID | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AA11458582 | |||||||||
| 出版者 | ||||||||||
| 出版者 | 秋田大学教育文化学部 | |||||||||
