| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2010-02-09 |
| タイトル |
|
|
タイトル |
EFFECT OF MODEST PERIOPERATIVE INTAKE OF IMMUNO-NUTRITION RICH IN ω -3 POLYUNSATURATED FATTY ACIDS ON IL-10 IN ESOPHAGEAL CANCER PATIENTS |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
esophagectomy |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
esophageal cancer |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
immuno-nutrition |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
IL-10 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
ω -3 Polyunsaturated Fatty Acids |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 作成者 |
Okuyama, Manabu
Motoyama, Satoru
Maruyama, Kiyotomi
Sasaki, Kenji
Sato, Yusuke
Ogawa, Jun-ichi
|
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background Recent trials have shown that perioperative administration of an immuno-enhancing diet can reduce the incidence of infectious complications and shorten hospital stay following elective surgery. The purpose of this study was to evaluate whether a relatively small perioperative intake of ω -3 polyunsaturated fatty acid (PUFA)-rich nutritional supplement modulates postoperative inflammatory responses. Methods Twenty-three patients with esophageal cancer were prospectively randomized into Treatment (n=11) and Control (n=12) groups. The former drank 2 packs (0.4 L) of a liquid diet that was supplemented with ω -3 fatty acids each day for 6 consecutive days prior to esophagectomy, while the latter drank a control liquid. In addition, both groups received postoperative enteral feeding with the same formula. The levels of human leukocyte antigen-DR (HLA-DR), interleukin (IL)-6 and IL-10 were measured, and polymorphonuclear cell and total lymphocyte counts were obtained. Results Plasma IL-10 levels were significantly (p<0.05) higher in the Treatment group than the Control group after beginning supplemental nutrition. By contrast, postoperative IL-6 levels tended to lower in the Treatment group, but the difference did not reach the level of significance. Conclusions Preoperative oral intake of a small amount of ω -3 PUFA-rich nutritional supplement increased postoperative IL-10 expression. |
|
言語 |
en |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 書誌情報 |
ja : 秋田医学
巻 36,
号 2,
p. 123-132,
発行日 2009-11-01
|
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
03866106 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN00009294 |
| 出版者 |
|
|
出版者 |
秋田医学会 |
|
言語 |
ja |
p123-132.pdf (873.3 kB)
