{"created":"2023-07-25T10:25:30.635149+00:00","id":5885,"links":{},"metadata":{"_buckets":{"deposit":"5134c8df-4e32-40b4-ac83-ca5943318f8f"},"_deposit":{"created_by":15,"id":"5885","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"5885"},"status":"published"},"_oai":{"id":"oai:air.repo.nii.ac.jp:00005885","sets":["597:633:634"]},"author_link":["16864","16865","16866","16867","16868"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicVolumeNumber":"8","bibliographic_titles":[{"bibliographic_title":"Physiological Reports","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Dehydration accrued during intense prolonged whole-body exercise in the heat compromises peripheral blood flow and cardiac output ((Q) over dot). A markedly reduced stroke volume (SV) is a key feature of the dehydration-induced cardiovascular strain, but whether the lower output of the heart is mediated by peripheral or cardiac factors remains unknown. Therefore, we repeatedly quantified left ventricular (LV) volumes, LV mechanics (LV twist, a marker of systolic muscle function, and LV untwisting rate, an independent marker of LV muscle relaxation), left intra-ventricular pressure gradients, blood volume and peripheral blood flow during 2 hr of cycling in the heat with and without dehydration (DEH: 4.0 +/- 0.2% body mass loss and EUH: euhydration control, respectively) in eight participants (three females and five males). While brachial and carotid blood flow, blood volume, SV, LV end-diastolic volume (LVEDV), cardiac filling time, systemic vascular conductance and (Q) over dot were reduced in DEH compared to EUH after 2 hr, LV twist and untwisting rate tended to be higher (p = .09 and .06, respectively) and intra-ventricular pressure gradients were not different between the two conditions (p = .22). Furthermore, LVEDV in DEH correlated strongly with blood volume (r = .995, p < .01), head and forearms beat volume (r = .98, p < .05), and diastolic LV filling time (r = .98, p < .05). These findings suggest that the decline in SV underpinning the blunted (Q) over dot with exercise-induced dehydration is caused by compromised LV filling and venous return, but not intrinsic systolic or diastolic LV function.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"John Wiley and Sons Inc"}]},"item_10001_relation_25":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.14814/phy2.14433","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.\n© 2020 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society."}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1724099666130":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"2051-817X","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"作成者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Watanabe, Kazuhito","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16864","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Stohr, EricJ.","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16865","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Akiyama, Koichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16866","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Watanabe, Sumie","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16867","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Gonzalez-Alonso, Jose","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16868","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-02-19"}],"displaytype":"detail","filename":"kyoA_2022_1.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"kyoA_2022_1.pdf","url":"https://air.repo.nii.ac.jp/record/5885/files/kyoA_2022_1.pdf"},"version_id":"0596f5f2-4c99-48bf-a9d5-9f92afe94526"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"blood flow","subitem_subject_scheme":"Other"},{"subitem_subject":"intraventricular pressure gradients","subitem_subject_scheme":"Other"},{"subitem_subject":"left ventricular volumes","subitem_subject_scheme":"Other"},{"subitem_subject":"twist and untwisting rate","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Dehydration reduces stroke volume and cardiac output during exercise because of impaired cardiac filling and venous return, not left ventricular function","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Dehydration reduces stroke volume and cardiac output during exercise because of impaired cardiac filling and venous return, not left ventricular function","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"15","path":["634"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-02-19"},"publish_date":"2023-02-19","publish_status":"0","recid":"5885","relation_version_is_last":true,"title":["Dehydration reduces stroke volume and cardiac output during exercise because of impaired cardiac filling and venous return, not left ventricular function"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-08-24T14:04:58.391743+00:00"}