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Novel extrapancreatic effects of incretin
http://hdl.handle.net/10295/00006191
http://hdl.handle.net/10295/00006191c48a5e3c-af8e-42cd-bdc2-f42b260f1461
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2023-02-19 | |||||
タイトル | ||||||
タイトル | Novel extrapancreatic effects of incretin | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
主題 | ||||||
主題Scheme | Other | |||||
主題 | Gastric inhibitory polypeptide | |||||
主題 | ||||||
主題Scheme | Other | |||||
主題 | Glucagon-like peptide-1 | |||||
主題 | ||||||
主題Scheme | Other | |||||
主題 | Incretin | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
作成者 |
Yamada, Yuichiro
× Yamada, Yuichiro× Tsukiyama, Katsushi× Sato, Takehiro× Shimizu, Tatsunori× Fujita, Hiroki× Narita, Takuma |
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内容記述 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The hormonal factors implicated as transmitters of signals from the gut to pancreatic -cells are referred to as incretins. Gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are incretins. In addition to the insulinotropic effects, we have shown, using the GIP receptor and GLP-1 receptor-deficient mice, that GIP and GLP-1 have direct actions on adipocytes and the kidney, respectively. Because GIP receptors and GLP-1 receptors are differentially expressed in a tissue-specific manner, GIP and GLP-1 have specific physiological activities, and further comprehensive characterization of the extrapancreatic actions of GIP and GLP-1 is anticipated, as dipeptidyl peptidaseIV inhibitors activate both GIP and GLP-1 signaling. | |||||
言語 | en | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
書誌情報 |
en : Journal of Diabetes Investigation 巻 7, 号 S1, p. 76-79, 発行日 2016 |
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収録物識別子 | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2040-1116 | |||||
出版者 | ||||||
出版者 | John Wiley and Sons Inc | |||||
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関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1111/jdi.12495 | |||||
権利情報 | ||||||
権利情報 | ©2016 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, LtdThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distributionin any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |