{"created":"2023-07-25T10:25:30.197472+00:00","id":5875,"links":{},"metadata":{"_buckets":{"deposit":"c167d680-895c-43ff-b4ee-1986a81a6629"},"_deposit":{"created_by":15,"id":"5875","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"5875"},"status":"published"},"_oai":{"id":"oai:air.repo.nii.ac.jp:00005875","sets":["611:939:940"]},"author_link":["16793","16794","16795","16796","16797"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"254","bibliographicPageStart":"251","bibliographicVolumeNumber":"4","bibliographic_titles":[{"bibliographic_title":"ACUTE MEDICINE & SURGERY","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Aim\nHuman serum albumin (HSA) is known for its multiple functions, such as maintenance of colloid osmotic pressure, transport of endogenous and exogenous substances, and antioxidation. The aim of this study was to measure the redox state and concentrations of β-d-glucan and endotoxin to compare the quality of 5% HSA preparations from two different manufacturers.\nMethods\nThe quality of 5% HSA preparations in two different pharmaceutical products (groups A and B) was compared in terms of the percentage of reduced and oxidized albumin and the contaminant level of β-d-glucan and endotoxin.\nResults\nThe percentage of human mercaptoalbumin in group A was significantly higher than that in group B (P < 0.01), whereas that of human non-mercaptoalbumin-2 in group A was significantly lower (P < 0.01). The concentration of β-d-glucan in group A was significantly lower than in group B (P < 0.01).\nConclusions\nThe present findings indicate the need for quality control of HSA preparations in applications involving the use of large volumes.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"John Wiley and Sons Inc"}]},"item_10001_relation_25":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1002/ams2.259","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© 2017 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes."}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1724099666130":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"2052-8817","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"作成者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakae, Hajime","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16793","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tomida, Kouki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16794","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kikuya, Yoshihiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16795","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okuyama, Manabu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16796","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Igarashi, Toshiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"16797","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-02-19"}],"displaytype":"detail","filename":"iA_2022_52.pdf","filesize":[{"value":"177.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"iA_2022_52.pdf","url":"https://air.repo.nii.ac.jp/record/5875/files/iA_2022_52.pdf"},"version_id":"5c0c8fea-6325-4574-9c7d-5d033ec997eb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Endotoxin","subitem_subject_scheme":"Other"},{"subitem_subject":"mercaptoalbumin","subitem_subject_scheme":"Other"},{"subitem_subject":"non-mercaptoalbumin","subitem_subject_scheme":"Other"},{"subitem_subject":"b-D-glucan","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Comparison of quality of human serum albumin preparations in two pharmaceutical products","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Comparison of quality of human serum albumin preparations in two pharmaceutical products","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"15","path":["940"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-02-19"},"publish_date":"2023-02-19","publish_status":"0","recid":"5875","relation_version_is_last":true,"title":["Comparison of quality of human serum albumin preparations in two pharmaceutical products"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-08-24T14:04:36.401044+00:00"}