@article{oai:air.repo.nii.ac.jp:00003458,
 author = {Yamada, Shunsuke and Aoki-Okazaki, Mieko and Toyono, Manatomo and Takahashi, Tsutomu},
 issue = {3/4},
 journal = {秋田医学, AKITA JOURNAL OF MEDICINE},
 month = {Mar},
 note = {Aims : To analyze functional status and left ventricular (LV) function of adolescents and adults before surgical closure of secundum atrial septal defect (ASD) during the most recent years.
Methods and Results : We investigated 68 patients before surgical ASD closure (surgical group) and 95 patients before device ASD closure (device group). New York Heart Association (NYHA) class and echocardiographic variables including LV and right ventricular (RV) size, LV and RV contractility, LV and RV Tei indices, and severity of mitral (MR) and tricuspid regurgitation (TR) were determined. Compared to the device group, the surgical group had worse NYHA class and decreased LV and RV function : greater LV volume and RV area, decreased LV and RV contractility, and increased LV Tei index (all p<0.05). The surgical group also showed higher occurrence of paroxysmal atrial fibrillation and greater MR and TR than the device group (all p<0.03). In the surgical group, TR severity was associated with worse NYHA class, whereas age at the time of surgery and RV end-diastolic area were associated with increased LV Tei index (all p<0.05).
Conclusion : Adolescents and adults before surgical closure of secundum ASD showed worse functional status and decreased LV function than those before device closure. In these patients before surgical ASD closure, greater TR severity was associated with worse functional status, whereas advanced-age and dilated RV were associated with LV dysfunction.},
 pages = {121--130},
 title = {Functional Status and Left Ventricular Function in Adolescents and Adults Before Device Closure},
 volume = {45},
 year = {2019}
}