@article{oai:air.repo.nii.ac.jp:00003332, author = {Tanaka , Oa and Maeda, Eri and Iwata, Toyoto and Murata, Katsuyuki}, issue = {2}, journal = {秋田医学, AKITA JOURNAL OF MEDICINE}, month = {Nov}, note = {A cross-sectional study was conducted to investigate the associations of ethanol intake, eating patterns, and sleep duration with serum triglycerides, LDL-cholesterol, and HDL-cholesterol levels, along with the contributions of these risk factors to lipids. Study participants (1,582 males and 424 females) who returned questionnaire forms and underwent the mandatory health checkup were enrolled. After adjusting for age, smoking, and exercise, the mean contribution ratio, representing the extent to which each independent variable explained lipid variations in a multiple regression analysis, in the males (and females) was 14% (9%) for body mass index, 2% (3%) for ethanol intake, 0.4% (1.3%) for a total of eating patterns, and 0.06% (0.06%) for sleep duration. Ethanol intake was associated with high triglycerides, high HDL-cholesterol, and low LDL-cholesterol. Breakfast-skipping was associated with high LDL-cholesterol in the males, snacking during work hours was associated with low triglycerides in the females, and dinner time irregularity was associated with low triglycerides in the males. Long sleep duration was associated with high triglycerides in the males. However, there were not significant interactions between drinking and eating patterns in the males or females. In conclusion, preventive measures of dyslipidemia should be taken in consideration of the priority based on the quantitative significance of risk factors. Although moderate drinking appears to reduce risks of hyper-LDL and hypo-HDL cholesterolemia, it may lead to hypertriglyceridemia, in addition to hepatocellular injury and hypertension.}, pages = {51--62}, title = {QUANTITATIVE SIGNIFICANCE OF ETHANOL INTAKE, EATING PATTERNS, AND SLEEP DURATION AFFECTING LIPID PROFILES IN MIDDLE-AGED EMPLOYEES}, volume = {45}, year = {2018} }