WEKO3
アイテム
Two Adaptogenic Humoral Lipoids Prepared in Mouse Given Various Stresses
https://doi.org/10.20569/00003454
https://doi.org/10.20569/000034544500153e-e802-4300-ac5a-99e3c55cce92
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
akitai44_2(63) (563.8 kB)
|
|
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2017-12-25 | |||||||
| タイトル | ||||||||
| タイトル | Two Adaptogenic Humoral Lipoids Prepared in Mouse Given Various Stresses | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 主題 | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | various stresses | |||||||
| 主題 | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | adaptogenic humoral lipoids | |||||||
| 主題 | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | serotonin | |||||||
| 主題 | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | noradrenaline | |||||||
| 主題 | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | neuronal activity | |||||||
| 主題 | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | cerebroside sulfates | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| ID登録 | ||||||||
| ID登録 | 10.20569/00003454 | |||||||
| ID登録タイプ | JaLC | |||||||
| アクセス権 | ||||||||
| アクセス権 | open access | |||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||
| 作成者 |
Masuda, Yutaka
× Masuda, Yutaka
|
|||||||
| 内容記述 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Stresses induce disaptation. Disadaptation induces depression and death. Animals prepare internal stress-coping substances for keeping their adaptation. Mouse given forced swimming stress produced an adaptogenic substance, in humoral lipoid fraction eluted with 100 mM NaCl, for keeping the physical strength, and mouse given repeated immunization stress prepared another substance, in humoral lipoid fraction eluted with 250 mM NaCl, for preventing the death. Mouse given various stresses may differently prepare these adaptogenic humoral lipoids. Depression closely relates to serotonergic and adrenergic neuronal activities. Production of the adaptogenic lipoids may be affected by antidepressants. Cerebrosides are lipoids primarily contented in brain sensing stresses. Cerebrosides may have adaptgenic activity same to the humoral lipoids. Mice were twice given immunization stress, given forced swimming stress or given fear stress on a raised platform, or not given the stresses as a control. Mice were also treated with a serotonin reuptake inhibitor clomipramine or a noradrenaline reuptake inhibitor maprotiline. A humoral lipoid preventing the death was produced in the fraction eluted with 100 mM NaCl of mice given the immunization stress, of mice given the forced swimming stress, or of mice treated with clomipramine or maprotiline. Another humoral lipoid preventing the death was deduced in the fraction eluted with 250 mM NaCl of mice given the immunization stress or of mice treated with maprotiline. Porcine brain cerebroside sulfates, fractionated with 100 mM NaCl and with 250 mM NaCl, dose-dependently prevented the death. These suggest that the adaptogenic humoral lipoids were cerebroside sulfates prepared via serotonergic and adrenergic neuronal activities, corresponding to quality of the stresses. | |||||||
| 言語 | en | |||||||
| 出版タイプ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
| 書誌情報 |
ja : 秋田医学 en : Akita journal of medicine 巻 44, 号 2, p. 63-67, 発行日 2017-11-30 |
|||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 0386-6106 | |||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AN00009294 | |||||||
| 出版者 | ||||||||
| 出版者 | 秋田医学会 | |||||||
| 言語 | ja | |||||||
