@article{oai:air.repo.nii.ac.jp:00002781,
 author = {FUJIWARA, Junichi and GOTO, Takashi and SHIBUYA, Tomomi and CHIBA, Mitsuru and OHSHIMA, Shigetoshi and MIURA, Kouichi and SATO, Wataru and DOHMEN, Takahiro and SAKAI, Toshitaka and SUGIMOTO, Yuko and MINAMI, Shinichiro and OHNISHI, Hirohide},
 issue = {1},
 month = {Jun},
 note = {Aim : To evaluate the usefulness of acoustic radiation force impulse (ARFI) in predicting hepatocellular
carcinoma (HCC) in patients with chronic hepatic disease (CHD).
Methods : A total of 230 patients participated in this study. They were subsequently classified
into the “HCC group” and the “non-HCC group”. We measured their liver stiffness and calculated
the mean shear wave velocity (SWV) using ARFI.
Results : The mean SWV was significantly higher in the HCC group than in the non-HCC
group. The cut-off value for the mean SWV with the best discrimination between the two groups
was 1.36 (m/s). The area under the receiver operating characteristic curve (AUROC) was
0.807. The AUROCs of the aspartate-aminotransferase-to-platelet ratio and Fibrosis 4 score
were 0.780, 0.728, respectively. The independent risk factors of HCC included the mean SWV
and age. A further analysis, based on the individual causes of CHD, found that among the HCV
and non-HBV and non-HCV (nBnC) cases, the mean SWV was significantly higher in the HCC
group than in the non-HCC group.
Conclusion : Measuring the SWV using ARFI was a reliable method for predicting HCC in CHD
patients, especially in HCV and nBnC patients.},
 pages = {39--49},
 title = {NON-INVASIVE METHOD FOR PREDICTING HEPATOCELLULAR CARCINOMA IN PATIENTS WITH CHRONIC HEPATIC DISEASE BY MEASURING THE SHEAR WAVE VELOCITY},
 volume = {43},
 year = {2016}
}