@article{oai:air.repo.nii.ac.jp:00002771, author = {MASUDA, Yutaka}, issue = {3/4}, journal = {秋田医学}, month = {Mar}, note = {Forced swimming in narrow space gives mice mental and physical stress. Their stress-coping behavior is recognized as hyperactivity climbing for escaping from the stressful situation, or motionlessness for keeping their physical strength. Mice given the stress would produce adaptogenic substances inducing the stress-coping behaviors. In the present study, conditions inducing motionlessness and humoral lipid inducing the behavior are investigated. The motionlessness of 9 weeks-old DDY mouse was increased in proportion to the given stress duration one day before. The motionlessness of mice with different age given the 10 minutes-stress one day before was increased corresponding to the age. Injection of lipid-fraction eluted with 100 mM NaCl obtained from sera of 9 weeks-old mice given the 15 minutes-stress increased motionlessness of mice without the previous stress. Fraction eluted with 100 mM NaCl of cerebroside sulfates also increased the motionlessness with a dose-dependent manner. These suggest that the humoral lipid with adaptogenic activity might be a cerebroside sulfate.}, pages = {119--123}, title = {A HUMORAL LIPID INDUCING STRESS-COPING BEHAVIOR MOTIONLESSNESS ON MOUSE GIVEN FORCED SWIMMING STRESS}, volume = {42}, year = {2016} }