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The clinical course of a gastrointestinal stromal tumor (GIST) diagnosed by endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA)
http://hdl.handle.net/10295/3130
http://hdl.handle.net/10295/3130f7b63b35-cc80-46e5-9cc4-079131022f65
| 名前 / ファイル | ライセンス | アクション |
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内容要旨及び審査結果要旨 (388.6 kB)
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本文 (440.0 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||
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| 公開日 | 2016-06-22 | |||||||||
| タイトル | ||||||||||
| タイトル | The clinical course of a gastrointestinal stromal tumor (GIST) diagnosed by endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA) | |||||||||
| 言語 | ||||||||||
| 言語 | jpn | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||
| 資源タイプ | doctoral thesis | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 別タイトル | ||||||||||
| その他のタイトル | 超音波内視鏡下穿刺吸引（EUS-FNA）により診断されたGISTの臨床経過 | |||||||||
| 作成者 |
関根, 匡成
× 関根, 匡成
× SEKINE, Masanari
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| 内容記述（抄録） | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Objectives: Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumor of the gastrointestinal tract. However, little is known about the clinical presentation of GIST, especially small lesions. The purpose of the present study was to clarify the efficacy of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for the diagnosis of GIST and to determine its clinical course. Methods: Pathological and clinical records of GIST extracted from our institutional database between 1996 and 2012 were reviewed. All GIST cases were diagnosed pathologically by surgical specimen or EUS-FNA. To examine the efficacy of EUS-FNA for the diagnosis of GIST, the pathological findings of EUS-FNA were compared with the surgical findings from resected cases. Next, to clarify the clinical presentation of GIST, imaging findings and changes in tumor size over time were evaluated in follow up. Results: Of 84 cases of GIST, 67 were resected surgically after EUS-FNA; tumor size was <20 mm in 19 patients, and ≥20 mm in 48 patients. For the diagnosis of small GIST<20 mm, sensitivity and positive predictive value of EUS-FNA were 81.3% and 100%, respectively. A total of 27 patients with GIST was follow up for more than 1 year. Tumor size increased significantly during follow up. However, generalized linear analysis showed that there was no significant relationship between tumor size and follow up period. Conclusions: The present results showed that even small GIST can be correctly identified by EUS-FNA. Moreover, size of small GIST increased significantly during follow up. |
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| 著者版フラグ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| DOI | ||||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | info:doi/10.1111/den.12333 | |||||||||
| 書誌情報 | 発行日 2016-06-01 | |||||||||
| 出版者 | ||||||||||
| 出版者 | 秋田大学 | |||||||||
| 著作権等 | ||||||||||
| 権利情報 | Wiley | |||||||||
| 備考 | ||||||||||
| 秋田大学審査学位論文(Digestive Endoscopy,27(1),p44-p52掲載論文の著者最終稿) | ||||||||||
| 学位名 | ||||||||||
| 学位名 | 博士(医学) | |||||||||
| 学位授与機関 | ||||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||||
| 学位授与機関識別子 | 11401 | |||||||||
| 学位授与機関名 | 秋田大学 | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2016-03-28 | |||||||||
| 学位授与番号 | ||||||||||
| 学位授与番号 | 乙第641号 | |||||||||
