{"created":"2023-07-25T10:23:06.269623+00:00","id":2702,"links":{},"metadata":{"_buckets":{"deposit":"753785df-4ae8-45bf-b29d-f569bcdbd5c8"},"_deposit":{"created_by":15,"id":"2702","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2702"},"status":"published"},"_oai":{"id":"oai:air.repo.nii.ac.jp:00002702","sets":["611:862:863:1085"]},"author_link":["9946"],"control_number":"2702","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1994-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"53","bibliographicPageStart":"47","bibliographicVolumeNumber":"21","bibliographic_titles":[{"bibliographic_title":"秋田医学","bibliographic_titleLang":"ja"}]}]},"item_10001_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"St ellate cells (vitamin A-storing cells，li pocytes，fa t-storing cells，It oc ells) exist in the perisinusoidal space of the hepatic lobule，a nd store 80% of retinoids in the whole body as retinyl palmitate in lipid droplets in the cytoplasm. Under physiological conditions，t hese cells play key roles in仕lecontrol of retinoid homeostasis ;th ey express specific receptors for retinol-binding protein (RBP) ，a b inding protein specific for retinol，o n their cell surface，a nd take up the complex of retinol and RBP by receptor-mediated endocytosis. However， under pathological conditions such as liver cirrhosis，lesecells lose retinoids，a nd synthesize al arge amount of extracellular matrix (ECM) components including collagen，pr oteoglycan and adhesive glycoproteins. The morphology of these cells also changes from. the star-shaped stellate cells to that of fibroblasts or myofibroblasts. The three-dimensional structure of ECM components reversibly regulates the morphology， pr oliferation，a nd functions of the stellate cells.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"秋田医学会","subitem_publisher_language":"ja"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1724099666130":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"03866106","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AN00009294","subitem_source_identifier_type":"NCID"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"作成者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"妹尾, 春樹","creatorNameLang":"ja"},{"creatorName":"SENOO, Haruki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9946","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-16"}],"displaytype":"detail","filename":"senoo3.pdf","filesize":[{"value":"1.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"senoo3.pdf","url":"https://air.repo.nii.ac.jp/record/2702/files/senoo3.pdf"},"version_id":"4b791004-52bb-49ce-86dc-6467b0357fb6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"perisinusoidal stellate cells","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"retinoids","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"retinol-binding protein","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"extracellullar matrix","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"肝臓星細胞の細胞生物学","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"肝臓星細胞の細胞生物学","subitem_title_language":"ja"},{"subitem_title":"Cell Biology of the Perisinusoidal Stellate Cell","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"15","path":["1085"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2016-04-20"},"publish_date":"2016-04-20","publish_status":"0","recid":"2702","relation_version_is_last":true,"title":["肝臓星細胞の細胞生物学"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-09-03T05:14:56.313404+00:00"}