{"created":"2023-07-25T10:23:05.007252+00:00","id":2673,"links":{},"metadata":{"_buckets":{"deposit":"0cb2da78-7290-4947-a874-c0d7a79c6c30"},"_deposit":{"created_by":3,"id":"2673","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2673"},"status":"published"},"_oai":{"id":"oai:air.repo.nii.ac.jp:00002673","sets":["611:939:940"]},"author_link":["9854","9855","9856"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1997-04-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"615","bibliographicPageStart":"604","bibliographicVolumeNumber":"16","bibliographic_titles":[{"bibliographic_title":"呼吸"}]}]},"item_10001_description_5":{"attribute_name":"内容記述（抄録）","attribute_value_mlt":[{"subitem_description":"肝小葉の実質細胞と内皮細胞の間(類洞周囲腔, いわゆるディッセ腔)には, 星細胞があり, レチノール結合蛋白質に対する特異的受容体を介したエンドサイトーシスによって, ビタミンAを細胞内に取り込み, 脂質滴の形で生体のビタミンA総量の約80%を貯蔵する。必要に応じてビタミンAを血漿中に分泌し, 生体のビタミンA恒常性維持の中心的役割を果たしている。しかし, 肝硬変等の病理的条件下では, ビタミンAを失い, 形態は星型から線維芽細胞様に変化し, 活発に分裂し, 大量の細胞外マトリックスを合成, 分泌する。また, この細胞の形態, 増殖, 機能は, 細胞外マトリックスの3次元構造によって可逆的に制御される。星細胞に似た細胞は肺にもあり, 肺胞中隔細胞とも呼ばれ, 肺胞中隔内の毛細血管周囲にあって, ビタミンAを取り込み貯蔵する。肺胞中隔にはほかに線維芽細胞と, 肺胞開口部に平滑筋細胞(肺胞筋線維芽細胞)が存在する。","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"レスピレーションリサーチファンデーション"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"02869314","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_26":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_value":"バックナンバーは、「呼吸研究」ホームページで検索、ＰＤＦのダウンロードが可能 http://www.respiration.jp/search/"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"妹尾, 春樹"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"佐藤, 充"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"今井, 克幸"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-16"}],"displaytype":"detail","filename":"senoo2.pdf","filesize":[{"value":"6.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"senoo2.pdf","url":"https://air.repo.nii.ac.jp/record/2673/files/senoo2.pdf"},"version_id":"e6d455a7-0bbe-4e44-b23e-7c84615a7410"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"肝臓星細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"肺胞中隔細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"コラーゲン","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞外マトリックス","subitem_subject_scheme":"Other"},{"subitem_subject":"ビタミンA","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"肝臓星細胞と肺胞中隔細胞","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"肝臓星細胞と肺胞中隔細胞"}]},"item_type_id":"10001","owner":"3","path":["940"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-04-20"},"publish_date":"2016-04-20","publish_status":"0","recid":"2673","relation_version_is_last":true,"title":["肝臓星細胞と肺胞中隔細胞"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-25T11:36:55.492179+00:00"}