@article{oai:air.repo.nii.ac.jp:00002575,
 author = {MASUDA, Yutaka and KOYOTA, Souichi and SUGIYAMA, Toshihiro},
 issue = {1},
 journal = {秋田医学},
 month = {Jun},
 note = {Anaphylaxis gives mice severe stress killing them. They could produce adaptogenic
substance for coping the stress. In the present study, the adaptogenic substance preventing from
mouse anaphylactic death was examined. Six-week-old male ddY mice were initially immunized
with 1 mg/kg of ovalbumin and second immunized with the same dosage 10 days after the initial
immunization. The mice further immunized with the same dosage at 5 days or 15 days after the
second immunization. All of the former were killed by the anaphylactic response, but none of the
latter were. Although reactivity of fucosylated antibodies inducing anaphylactic response was
not different in the former sera and the latter sera, a lipid preventing from anaphylactic death was
found in fraction eluted with 300 mM NaCl of the latter sera. The present findings suggest that
the lipid had an adaptogenic activity against severe stress induced by anaphylactic response, and
was produced in late phase of the second immune response.},
 pages = {37--41},
 title = {A HUMORAL LIPID PREVENTING FROM MOUSE ANAPHYLACTIC DEATH},
 volume = {42},
 year = {2015}
}