@article{oai:air.repo.nii.ac.jp:00002574,
 author = {SHIMBO, Mai and KOSAKA, Toshimitsu and FUSHIMI, Etsuko and KOYAMA, Takashi and IINO, Kenji and WATANABE, Hiroyuki and ITO, Hiroshi},
 issue = {1},
 journal = {秋田医学会},
 month = {Jun},
 note = {Objective : The aim of this study was to investigate whether cardiac autonomic function measured
by heart rate variability (HRV) indices are related to quality of life (QOL) improvements in
patients with acute myocardial infarction (AMI) treated by percutaneous coronary intervention.
Methods : We enrolled 20 consecutive patients with AMI. Measures of HRV, obtained from
both frequency and time domain analyses using 24-h Holter monitoring before discharge, were as
follows : low and high frequency (HF) domain measures, the square root of the mean squared differences
of successive R-R intervals (rMSSD), and the percentage of differences between adjacent
normal R-R intervals >50 ms for the whole analysis (pNN50). QOL was determined by
physical and mental component summary (PCS and MCS, respectively) scores derived from the
Japanese Medical Outcomes Study 36-item Short Form Health Survey before and 6 months after
discharge.
Results : The subjects showed significant improvement in the MCS, but not the PCS score.　
There were also positive correlations between the parasympathetic parameters of HF, rMSSD,
and pNN50 and the change in MCS score. In a multivariate analysis, rMSSD was found to be
independently associated with the change in MCS score.
Conclusions : Parasympathetic tone, as measured by HRV, is independently associated with
QOL, which emphasizes the role of cardiac autonomic function on QOL in patients with AMI.},
 pages = {29--36},
 title = {QUALITY OF LIFE AND HEART RATE VARIABILITY FOLLOWING ACUTE MYOCARDIAL INFARCTION},
 volume = {42},
 year = {2015}
}