@article{oai:air.repo.nii.ac.jp:00002158, author = {熊谷, 彩子 and 小泉, 幸央 and 川越, 政美 and 小代田, 宗一 and 杉山, 俊博 and Kumagai, Ayako and Koizumi, Yukio and Kawagoe, Masami and Koyota, Souichi and Sugiyama, Toshihiro}, issue = {2}, journal = {秋田医学}, month = {Nov}, note = {The medicinal mushroom Inonotus obliquus is a traditional and widely used multi-functional fungus. In the present study, the lipophilic fraction of Inonotus obliquus were investigated for their antioxidative activity with hydroxyl radical scavenging activity assays. As a result, two acidic materials had higher antioxidative activity than basic or neutral materials. Furthermore, antioxidative acidic materials including organic acids were isolated by silica gel column chromatography and subsequent preparative high-performance liquid chromatography. Two purified antioxidants, designated compound 1 and 2, were identified as vanillic acid and syringic acid, respectively. Vanillic acid and syringic acid were showed the antioxidative activities with IC_50 values of 59.0 and 2.8 μg/ml, respectively.}, pages = {113--119}, title = {カバノアナタケ(Inonotus obliquus)由来の抗酸化成分の同定}, volume = {40}, year = {2013} }