{"created":"2024-01-10T02:36:38.822520+00:00","id":2000072,"links":{},"metadata":{"_buckets":{"deposit":"c9238b1d-eacd-4177-9951-2789e109a557"},"_deposit":{"created_by":15,"id":"2000072","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000072"},"status":"published"},"_oai":{"id":"oai:air.repo.nii.ac.jp:02000072","sets":["611:862:863:1704846062939"]},"author_link":[],"item_10001_biblio_info_7":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-11-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"79","bibliographicPageStart":"73","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"秋田医学","bibliographic_titleLang":"ja"},{"bibliographic_title":"Akita journal of medicine","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Purpose : Cytomegalovirus （CMV） infection is the most frequent congenital infection. Although symptomatic congenital CMV infection is expected to affect 15 to 30 patients in Akita over a 10-year period, no comprehensive survey has been conducted.\nSubjects and Methods : A retrospective survey of medical records of children with symptomatic congenital CMV infection born during 2012-2022 in 14 secondary and tertiary medical faculties in Akita was conducted.\nResults : Six patients were identified.　Four cases were suspected owing to elevated direct bilirubin or hepatobiliary enzymes, whereas the other two were suspected due to elevated maternal CMV antibody. Four and two patients were diagnosed by detection of blood or urine CMV DNA and elevated serum CMV IgM, respectively.　Abnormal brain findings were observed in three patients. Antiviral therapy （ganciclovir or valganciclovir） was provided to five patients. Among the treated subjects, two patients exhibited developmental delay and three patients exhibited hearing loss.\nConclusion : Many symptomatic congenital CMV infections remain possibly undiagnosed. Since early antiviral therapy has been expected to reduce the neurological sequelae, early diagnosis is increasingly important.　Therefore, it is necessary to establish an effective screening system for early detection of congenital CMV infections in Akita.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_identifier_registration":{"attribute_name":"identifier_registration","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.20569/0002000072","subitem_identifier_reg_type":"JaLC"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"秋田医学会","subitem_publisher_language":"ja"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1724099666130":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"0386-6106","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"AN00009294","subitem_source_identifier_type":"NCID"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"作成者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"秋山, 光司","creatorNameLang":"ja"},{"creatorName":"Akiyama, Koji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"安達, 裕行","creatorNameLang":"ja"},{"creatorName":"Adachi, Hiroyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"伊藤, 誠人","creatorNameLang":"ja"},{"creatorName":"Ito, Masato","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"加藤, 明英","creatorNameLang":"ja"},{"creatorName":"Kato, Akie","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"高橋, 勉","creatorNameLang":"ja"},{"creatorName":"Takahashi, Tsutomu","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-01-10"}],"filename":"akitai50_2(73).pdf","filesize":[{"value":"794 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://air.repo.nii.ac.jp/record/2000072/files/akitai50_2(73).pdf"},"version_id":"0cccc798-abdc-46a8-9ebc-b1962068750c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"hearing loss","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"infant","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"screening","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"valganciclovir","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"過去10 年間の秋田県における症候性先天性 サイトメガロウイルス感染症の発生状況ならびに臨床的検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"過去10 年間の秋田県における症候性先天性 サイトメガロウイルス感染症の発生状況ならびに臨床的検討","subitem_title_language":"ja"},{"subitem_title":"Symptomatic congenital cytomegalovirus infections in Akita in the past 10 years","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"15","path":["1704846062939"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-01-10"},"publish_date":"2024-01-10","publish_status":"0","recid":"2000072","relation_version_is_last":true,"title":["過去10 年間の秋田県における症候性先天性 サイトメガロウイルス感染症の発生状況ならびに臨床的検討"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-09-20T03:00:36.962931+00:00"}