{"created":"2024-01-10T02:09:21.031445+00:00","id":2000071,"links":{},"metadata":{"_buckets":{"deposit":"13adab4d-c923-467a-b674-e7f64cb13559"},"_deposit":{"created_by":15,"id":"2000071","owner":"15","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2000071"},"status":"published"},"_oai":{"id":"oai:air.repo.nii.ac.jp:02000071","sets":["611:862:863:1704846062939"]},"author_link":[],"item_10001_biblio_info_7":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-11-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"71","bibliographicPageStart":"63","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"秋田医学","bibliographic_titleLang":"ja"},{"bibliographic_title":"Akita journal of medicine","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Background : Aneuploid embryos have also been reported to expand, albeit at a slower rate than euploid embryos. Accordingly, we hypothesized that embryonic expansion is related to chromosomal homogeneity. The aim of this study was to investigate why blastocyst expansion is an independent predictor of pregnancy during blastocyst transfer cycles in assisted reproductive technology. This retrospective preliminary study was performed using 103 surplus embryos from 53 couples who opted for assisted reproductive technology at a single center in 2019.\nResults : The inner diameter of euploid blastocysts (187.6±10.9 μm, n=23) and aneuploid blastocysts (184.0±14.2 μm, n=31) did not differ significantly. However, the inner diameter of mosaic blastocysts (178.6±11.8 μm, n=49) was significantly smaller (P<0.01) than that of euploid blastocysts. The inner diameter of blastocysts and patient characteristics or morphological grading of blastocysts did not significantly differ. In the multivariate analysis, the inner diameter of blastocysts was an independent variable predicting mosaic blastocysts (adjusted odds ratio : 0.95 ; 95% confidence interval : 0.92-0.99 ; P<0.01).\nConclusion : The day 6 blastocyst-expansion ability reflects chromosomal mosaicism of the trophectoderm independent of patient characteristics and the morphological grading of blastocysts.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_identifier_registration":{"attribute_name":"identifier_registration","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.20569/0002000071","subitem_identifier_reg_type":"JaLC"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"秋田医学会","subitem_publisher_language":"ja"}]},"item_10001_version_type_20":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1724099666130":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"0386-6106","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"AN00009294","subitem_source_identifier_type":"NCID"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"作成者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hasegawa, Hisataka","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Takahashi, Kazumasa","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kobayashi, Tatsuya","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Iwasawa,Takuya","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Fujishima, Akiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Togashi, Kazue","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kenichi Makino","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Shirasawa, Hiromitsu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Miura, Hiroshi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Sato, Wataru","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kumazawa, Yukiyo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kobayashi, Junichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Terada, Yukihiro","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-01-10"}],"filename":"akitai50_2(63).pdf","filesize":[{"value":"692 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://air.repo.nii.ac.jp/record/2000071/files/akitai50_2(63).pdf"},"version_id":"7a13bd2b-dd08-4159-b335-f6afff8a5a67"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"aneuploidy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"blastocyst","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mosaicism","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"nextgeneration sequencing","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"reproduction","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"DIAMETER OF HUMAN DAY 6 BLASTOCYSTS REFLECTS THE GENETIC HOMOGENEITY OF TROPHECTODERM COMPONENTS","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"DIAMETER OF HUMAN DAY 6 BLASTOCYSTS REFLECTS THE GENETIC HOMOGENEITY OF TROPHECTODERM COMPONENTS","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"15","path":["1704846062939"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-01-10"},"publish_date":"2024-01-10","publish_status":"0","recid":"2000071","relation_version_is_last":true,"title":["DIAMETER OF HUMAN DAY 6 BLASTOCYSTS REFLECTS THE GENETIC HOMOGENEITY OF TROPHECTODERM COMPONENTS"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-09-20T03:00:34.601161+00:00"}