{"created":"2023-07-25T10:22:20.568548+00:00","id":1680,"links":{},"metadata":{"_buckets":{"deposit":"cd4ede4c-1407-4ca4-9150-d82b8f494182"},"_deposit":{"created_by":3,"id":"1680","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"1680"},"status":"published"},"_oai":{"id":"oai:air.repo.nii.ac.jp:00001680","sets":["611:612:874:882"]},"author_link":["6163","6165","6162","6164","6161","6166"],"item_10002_alternative_title_34":{"attribute_name":"別タイトル","attribute_value_mlt":[{"subitem_alternative_title":"Immunohistochemical localization and seasonal variation in orexin innervation in the hypothalamus of two hibernators"}]},"item_10002_biblio_info_36":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"37","bibliographicPageStart":"31","bibliographicVolumeNumber":"19","bibliographic_titles":[{"bibliographic_title":"秋田大学大学院医学系研究科保健学専攻紀要"}]}]},"item_10002_description_29":{"attribute_name":"内容記述（抄録）","attribute_value_mlt":[{"subitem_description":"摂食飲水行動がほとんどない冬眠期では,冬眠動物は様々な生理現象を低下させエネルギー消費を抑えて生活している.適切な摂食行動は,摂食中枢と満腹中枢によって行われている.この制御は複雑な神経系によるが,摂食中枢と満腹中枢はそれぞれ視床下部の外側核と腹内側核にあるとされてきた.しかし,この部位に局在する神経伝達物質が特定されなかったためにこの分野の研究が進まなかった.近年,この部位に局在するオレキシンの発見により,この部位の役割が明らかになってきた.本研究は,オレキシンの抗体を用いて,概年リズムにおける視床下部の様々な領域でのオレキシン免疫陽性部位の形態学的変化について明らかにし,冬眠導入の引き金とひとつと考えられる摂食行動と冬眠機構との関係について検討した. \nHibernation is a seasonal phenomenon to which some mammalian hibernators respond by temporarily suppressing their vital parameters in response to low ambient temperature and shortages of food and water. Appropriate feeding behavior is regulated by the feeding centre and satiety centre. This is regulated by a complex nervous system, but the feeding centre and satiety centre are each located in the hypothalamus lateral nuclei and the ventromedial nucleus. However, as the neurotransmitters localised here have not been identified, research has not progressed. Recently the roles of these sites have been clarified following the discovery of localised orexins. This study uses orexin antibodies to clairfy the morphological changes due to circannual rhythms in orexin immunopositive sites in various regions of the hypothalamus, and investigates the connection between hibernation and feeding behaviour, thought to be a hibernation trigger.","subitem_description_type":"Other"}]},"item_10002_publisher_30":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"秋田大学大学院医学系研究科保健学専攻"}]},"item_10002_source_id_27":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1884-0167","subitem_source_identifier_type":"ISSN"}]},"item_10002_source_id_35":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA12447617","subitem_source_identifier_type":"NCID"}]},"item_10002_version_type_37":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大友, 和夫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"福原, 紅子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"呉, 毅"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OHTOMO, Kazuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"FUKUHARA, Kohko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"WU, Yi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-16"}],"displaytype":"detail","filename":"hoken19-1(31).pdf","filesize":[{"value":"845.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"hoken19-1(31).pdf","url":"https://air.repo.nii.ac.jp/record/1680/files/hoken19-1(31).pdf"},"version_id":"d0c38496-1662-482e-a90d-c62046e8aa61"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"概年リズム","subitem_subject_scheme":"Other"},{"subitem_subject":"冬眠","subitem_subject_scheme":"Other"},{"subitem_subject":"視床下部","subitem_subject_scheme":"Other"},{"subitem_subject":"オレキシン","subitem_subject_scheme":"Other"},{"subitem_subject":"免疫組織化学","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"冬眠動物視床下部におけるオレキシン免疫陽性部位の季節変化について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"冬眠動物視床下部におけるオレキシン免疫陽性部位の季節変化について"}]},"item_type_id":"10002","owner":"3","path":["882"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-07-27"},"publish_date":"2011-07-27","publish_status":"0","recid":"1680","relation_version_is_last":true,"title":["冬眠動物視床下部におけるオレキシン免疫陽性部位の季節変化について"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-25T11:47:52.620097+00:00"}