@article{oai:air.repo.nii.ac.jp:00001560,
 author = {IZUMI, Manabu and KIBIRA, Satoshi and WATANABE, Hiroyuki and TSUYA, Hiroyuki and [ほか]},
 issue = {3-4},
 journal = {秋田医学},
 month = {Dec},
 note = {Objectives: The purpose of this study is to analyze factors that influence the gap of
opening timing between the mitral valve (MV) and the tricuspid valve (TV) in
patients with dilated cardiomyopathy (DCM).
Background: The DCM patients with heart failure often show shorter left ventricular
(LV) isovolumic relaxation time (IRT) and longer right ventricular (RV) IRT, which
may influence the gap of opening timing between TV and MV.
Method: We evaluated consecutive 34 patients with DCM. The time between QRS
initial and TV opening (Q-T time), and that between QRS initial and MV opening (QM
time) were measured by pulsed Doppler recording of each ventricular inflow. The
time interval between MV and TV opening (M-T time) was determined by subtracting
Q-M time from Q-T time. In addition, the other Doppler time intervals including preejectional
period, ejection time, IRT were determined. We analyzed the relation
between Doppler time intervals and factors including NYHA classification and rightsided
cardiac pressure.
Result: There is significant relationship (p <0.001) between M-T time and PCWP
(r=0.65), and NYHA (rs=0.67), respectively. The Ll IRT determined by subtraction
of LV IRT from RV IRT, correlated significantly with M-T time (r=0.83, p<O.OOl),
however, the difference between LV and RV in PEP and ET did not correlated
significantly with M-T time.
Conclusion: The gap of opening timing between TV and MV, determined as M-T time,
correlates strongly with LlIRT and also the severity of congestive heart failure in DCM
patients.},
 pages = {201--209},
 title = {Determinants of Severity in Dilated Cardiomyopathy : The Gap of Tricuspid and Mitral Valve Opening},
 volume = {31},
 year = {2004}
}