{"created":"2023-07-25T10:22:14.582365+00:00","id":1544,"links":{},"metadata":{"_buckets":{"deposit":"6311ffe6-77fe-4da0-8eaa-c9a8d4117a10"},"_deposit":{"created_by":3,"id":"1544","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"1544"},"status":"published"},"_oai":{"id":"oai:air.repo.nii.ac.jp:00001544","sets":["611:862:863:864"]},"author_link":["5592","5590","5593","5589","5591"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-05-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"81","bibliographicPageStart":"71","bibliographicVolumeNumber":"31","bibliographic_titles":[{"bibliographic_title":"秋田医学"}]}]},"item_10001_description_5":{"attribute_name":"内容記述（抄録）","attribute_value_mlt":[{"subitem_description":"Mammalian hibernators experience drastic changes in vital signs such as\nbody temperature, respiratory rate, and heart rate during hibernation because of periodic\narousals during which vital signs return to non-hibernating levels. The carotid body, an\narterial chemoreceptor organ regulating respiration, contains several neuroactive substances.\nHowever, little is known about changes of neuroactive substances in the carotid\nbody during hibernation. Immunohistochemical study using antibodies against neuroactive\nsubstances, namely tyrosine hydroxylase (TH), methionine-enkephalin (MetEnk)\n, and gamma-aminobutyric acid (GABA) showed that immunoreactivities for TH,\nMet-Enk and GABA in type I cells of carotid bodies in hibernating animals increased in\ncomparison with those in non-hibernating ones. Furthermore, we monitored vital signs\nof chipmunks during arousal from hibernation, and found that the heart rate increased\nexponentially and the respiratory rate increased linearly as body temperature gradually\nincreased. Subsequent examination of TH-immunoreactivity in carotid bodies during\narousal showed that the TH-immunoreactivity decreased during the course of arousal\nfrom hibernation. The type I cells enlarged in size during hibernation, but the sinusoidal\ncapillaries around them did not. These results suggest that several neuroactive substances\nin type I cells playa significant role in the regulation of chemoreception during\nthe hibernating physiological state.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"秋田医学会"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00009294","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03866106","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"FUKUHARA, Kohko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YOSHIZAKI, Katsuaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"WU, Yi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SENOO, Haruki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OHTOMO, Kazuo"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-02-16"}],"displaytype":"detail","filename":"akigaku31-1g.pdf","filesize":[{"value":"693.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"akigaku31-1g.pdf","url":"https://air.repo.nii.ac.jp/record/1544/files/akigaku31-1g.pdf"},"version_id":"abd74d20-83c6-4760-9831-83ab4c740f03"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"TH","subitem_subject_scheme":"Other"},{"subitem_subject":"neuroactive substance","subitem_subject_scheme":"Other"},{"subitem_subject":"hibernation","subitem_subject_scheme":"Other"},{"subitem_subject":"carotid body","subitem_subject_scheme":"Other"},{"subitem_subject":"immunohistochemistry","subitem_subject_scheme":"Other"},{"subitem_subject":"chipmunk","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Immunohistochemical and Morphological Changes in Chipmunk Carotid Body during Hibernaiton","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Immunohistochemical and Morphological Changes in Chipmunk Carotid Body during Hibernaiton"}]},"item_type_id":"10001","owner":"3","path":["864"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-01-18"},"publish_date":"2009-01-18","publish_status":"0","recid":"1544","relation_version_is_last":true,"title":["Immunohistochemical and Morphological Changes in Chipmunk Carotid Body during Hibernaiton"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-25T11:50:06.658652+00:00"}