@article{oai:air.repo.nii.ac.jp:00001473,
 author = {大友, 和夫 and 福原, 紅子 and 吉崎, 克明 and OHTOMO, Kazuo and FUKUHARA, Kohko and YOSHIZAKI, Katsuaki},
 issue = {2},
 journal = {秋田大学医療技術短期大学部紀要},
 month = {Jan},
 note = {The carotid body as an arterial chemosensory organ regulates respiration, and its parenchymal cells
contain several neuropeptides. Therefore, it would be of interest to identify differences in the
physiological state and the distribution of several neuropeptides between hibernating and nonhibernating
animals. We examined immunohistochemically the distribution of several neuropeptides in
the carotid bodies of two mammalian species to study the role of the organ in the hibernation,
focusing on differences in the vital signs between the hibernation and nonhibernation periods.
Hibernation represents a physiological adaptation to the severe environment during winter. Vital
signs such as respiration rate, heart rate and body temperature in hibernating animals are markedly
decreased and the depression and heart rate in particular could result in hypoxia.
Respiration rate and heart rate during hibernation were less than one tenth of those during nonhibernation.
Intense immunoreactivities for tyrosine hydroxylase(TH) and glutamate(Glu) was observed as small
groups in the glomus cells of the carotid body during the non-hibernation phase. In the hibenating
animals, mild. methionin-enkephaline(Met-Enk) immunoreactivities were evident in almost all glomus
cells and some nerve fibers.
In the electron microscopic observation,the visible difference of the size and morphology observed
the mitochondoria in glomus cells of the both animals.},
 pages = {109--116},
 title = {冬眠動物における頚動脈小体の季節変化について},
 volume = {7},
 year = {1999}
}