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oai:air.repo.nii.ac.jp:00001772 2024-08-25T08:47:56Z 611:862:863:898

STEREOTACTIC IRRADIATION FOR BRAIN METASTASES : ANALYSIS OF PROGNOSTIC FACTORS IN SURVIVAL Izumi, Junichi Watanabe, Osamu Koga, Makoto Anbai, Akira Suzuki, Akira Hashimoto, Manabu open access stereotactic radiotherapy brain metastases prognostic factors Stereotactic radiotherapy (SRT) has become an established therapeutic option for patients with brain metastases. The purpose of this study was to evaluate the effcacy of SRT for brain metastases and to identify prognostic factors affecting survival. We analyzed 74 patients with brain metastases encountered at Akita University from June 2000 to February 2003. The survival rate was assessed by the Kaplan-Meire method, and the significance of differences was determined with the log-rank test. The Cox regression analysis was used adjusting for factors including age, gender, Karnofsky performance status (KPS), tumor volume, tumor number, extracranial disease status. This study showed the median survival after SRT for the whole group was 7.9 months, and KPS and extracranial disease status are independent factors for survival. Patients with KPS <70 and extracranial progressive disease had a very poor outcome with a median survival of 3.3 months, and are unlikely to benefit from SRT 秋田医学会 2011-12-01 eng journal article VoR http://hdl.handle.net/10295/1829 https://air.repo.nii.ac.jp/records/1772 秋田医学 38 2 49 55 https://air.repo.nii.ac.jp/record/1772/files/akitai38(49).pdf application/pdf 710.2 kB 2017-02-16