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oai:air.repo.nii.ac.jp:00001585 2023-07-25T11:18:53Z 590:591:765:869

ダンシルグリシン修飾シクロデキストリンの生理活性物質に対する分子認識センサー能 Host-Guest Sensory System of Dansyl-Modified Cyclodextrin for Detecting Bioactive-Compounds by Dansyl Fluoresence 濱田, 文男 石川, 匡子 秋山, 葉子 上野, 昭彦 HAMADA, Fumio ISHIKAWA, Kyoko AKIYAMA, Yoko UENO, Akihiko シクロデキストリン Cyclodextrin Dansyl-modified β-, γ-cyclodextrins (1 and 2) have been prepared as a sensor for detecting bioactive-organic compounds such as steroids and alkaloids. 1 shows pure monomer fluorescence whose intensity is decreased upon addition of guest species. However, 2 shows two types of pure monomer fluorescence, that is, one is the same for the case of 1, the other is whose intensities is enhanced upon addition of guest species. This guest-induced variation in the fluorescence intensity suggests that the dancylglycine moiety acts as a spacer which enables the cyclodextrin to form 1 : 1 host complexing by narrowing the large γ-cyclodextrin cavity. The value △I/I°, where I and ro are fluorescence intensities in the presence and absence of a guest and △I is 1°-I is fluorescence parameter. 1 exhibits higher selective and sensitive molecular recognition ability for steroids and alkaloids except for lithocholic acid than does 2. 秋田大学鉱山学部 1993-10-29 jpn departmental bulletin paper VoR http://hdl.handle.net/10295/1585 https://air.repo.nii.ac.jp/records/1585 03898040 AN00010307 秋田大学鉱山学部研究報告 14 19 24 https://air.repo.nii.ac.jp/record/1585/files/kozan14a.pdf application/pdf 481.0 kB 2017-02-16