2026-03-11T07:02:04Z https://air.repo.nii.ac.jp/oai

oai:air.repo.nii.ac.jp:00001560 2024-08-25T08:45:27Z 611:862:863:866

Determinants of Severity in Dilated Cardiomyopathy : The Gap of Tricuspid and Mitral Valve Opening IZUMI, Manabu KIBIRA, Satoshi WATANABE, Hiroyuki TSUYA, Hiroyuki [ほか] open access dilated cardiomyopathy heart failure mitral valve tricuspid valve isovolumic relaxation Objectives: The purpose of this study is to analyze factors that influence the gap of opening timing between the mitral valve (MV) and the tricuspid valve (TV) in patients with dilated cardiomyopathy (DCM). Background: The DCM patients with heart failure often show shorter left ventricular (LV) isovolumic relaxation time (IRT) and longer right ventricular (RV) IRT, which may influence the gap of opening timing between TV and MV. Method: We evaluated consecutive 34 patients with DCM. The time between QRS initial and TV opening (Q-T time), and that between QRS initial and MV opening (QM time) were measured by pulsed Doppler recording of each ventricular inflow. The time interval between MV and TV opening (M-T time) was determined by subtracting Q-M time from Q-T time. In addition, the other Doppler time intervals including preejectional period, ejection time, IRT were determined. We analyzed the relation between Doppler time intervals and factors including NYHA classification and rightsided cardiac pressure. Result: There is significant relationship (p <0.001) between M-T time and PCWP (r=0.65), and NYHA (rs=0.67), respectively. The Ll IRT determined by subtraction of LV IRT from RV IRT, correlated significantly with M-T time (r=0.83, p<O.OOl), however, the difference between LV and RV in PEP and ET did not correlated significantly with M-T time. Conclusion: The gap of opening timing between TV and MV, determined as M-T time, correlates strongly with LlIRT and also the severity of congestive heart failure in DCM patients. 秋田医学会 2004-12-01 eng journal article VoR http://hdl.handle.net/10295/1557 https://air.repo.nii.ac.jp/records/1560 03866106 AN00009294 秋田医学 31 3-4 201 209 https://air.repo.nii.ac.jp/record/1560/files/akigaku31-34e.pdf application/pdf 523.5 kB 2017-02-16